Map and Directions


The Sikeston Depot Museum is located at 116 West Malone Ave in Historic Downtown Sikeston


From I55 take exit 67. Follow Malone Ave due West for 3-1/2 miles.


From US Highway 60 take US Highway 61 North (aka Main Street) 2 miles to Malone Ave. Turn West on Malone for 3/4 miles.